In situ structure and organization of the influenza C virus surface glycoprotein

In situ structure and organization of the influenza C virus surface glycoprotein

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Magnetic Pump Influenza C virus contains a single surface glycoprotein, the haemagglutinin-esterase-fusion (HEF) protein, that mediates receptor binding, receptor destruction, and membrane fusion activities.Here, the authors apply electron cryotomography of whole virus together with subtomogram averaging to determine the HEF structure and lattice organisation on the Bosch DWB98JQ50B Serie 6 Built In 90cm 5 Speeds A+ Chimney Cooker Hood viral membrane and they discuss mechanistic implications for virus budding and membrane fusion.